The Cleveland Guardians (40-48) and the Houston Astros (55-35) open a 3-game series Monday at Daikin Park in Houston. First pitch is scheduled for 8:10 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Guardians vs. Astros odds and make our expert MLB picks and predictions for the best bets.

The Astros swept the Dodgers at Chavez Ravine over the weekend. They have now won five of their last six to maintain control of the American League West. Sunday, Jose Altuve went yard, and Ryan Gusto allowed just one run over six innings to earn his sixth win of the season.

After sweeping the Los Angeles Dodgers, the Astros return home to open a series against the Cleveland Guardians who have lost 10 in a row.