Histones are crosslinked with DNA (histone-DPC) following formaldehyde exposure, leading to the malfunction of cellular processes such as transcription. A team of researchers at Nagoya University in ...

Understanding protein–ligand interactions is fundamental to molecular biology and biochemistry. These interactions are at the heart of many cellular processes, from enzyme catalysis to signal ...

A team of researchers at Nagoya University in Japan has discovered that aldehydes are metabolic byproducts associated with premature aging. Published in Nature Cell Biology, their findings reveal ...

Aldehyde dehydrogenase 2 (ALDH2) is an important enzyme that detoxifies harmful aldehydes produced in the body. While it is best known for metabolizing acetaldehyde—an aldehyde increased by ...

Ketones are in equilibrium with a form known as an enol. The name enol derives from the fact that enols are a combination of a carbonyl (C=O) containing group, such as an aldehyde or ketone and an ...