Animal Welfare Institute

Wickremsinhe, E. R., Perkins, E. J. 2015. Using dried blood spot sampling to improve data quality and reduce animal use in mouse pharmacokinetic studies. JAALAS. 54(2), 139-144.

Traditional pharmacokinetic analysis in nonclinical studies is based on the concentration of a test compound in plasma and requires approximately 100 to 200 μL blood collected per time point. However, ...
Animal Welfare Institute

Meyer, N., Kröger, M., Thümmler, J. et al. 2020. Impact of three commonly used blood sampling techniques on the welfare of laboratory mice: Taking the animal’s perspective ...

Laboratory mice are the most frequently used animals in biomedical research. In accordance with guidelines for humane handling, several blood sampling techniques have been established. While the ...