Christian McCaffrey battles his former team in primetime as the 49ers face the Panthers in the Week 12 finale.

Watch the best plays from San Francisco 49ers RB Christian McCaffery's 142-yard game against the Carolina Panthers in Week 12 ...

Christian McCaffrey National Football League San Francisco 49ers Top Plays NFL - San Francisco 49ers vs. Arizona Cardinals - 11/16/2025 ...

Christian McCaffrey turned in another strong performance on Monday night, leading the San Francisco 49ers to a 20-9 victory ...

"We do it all the time in practice, so it's not a big deal," Trent Williams said of McCaffrey's untouched TD. "But yeah, it's ...

San Francisco 49ers running back Christian McCaffrey explained the significance of Roger Craig and Frank Gore's impact on his ...

San Francisco 49ers running back Christian McCaffrey rushes for a 12-yard gain against the Arizona Cardinals. Cleveland ...

It wasn’t pretty, and it definitely wasn’t smooth, but the San Francisco 49ers got the win they needed on Monday Night ...

Head Coach Kyle Shanahan highlighted standout performances on both sides of the ball, and emphasized the growth and execution ...

This game is particularly poignant as it represents the first time the Panthers will face McCaffrey since trading him to the 49ers. Known for his exceptional dual-threat capability, McCaffrey has ...

In the aftermath of McCaffrey's departure, the Panthers surprisingly did not falter in their run game. Under interim coach Steve Wilks, the team adopted a more straightforward rushing strategy, ...

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since ...