Splenomegaly is one of the characteristic signs of an overactive spleen. It can cause platelets to pool inside of your spleen and cause thrombocytopenia. Thrombocytopenia is when you have a low ...

Isabel Casimiro, MD, PhD, is an endocrinologist at the University of Chicago in Illinois. As a physician-scientist in molecular biology, she uses her research on diabetes, lipid disorders, ...

A vigorous, healthy-appearing newborn boy is brought to the local emergency room for evaluation after a spontaneous home delivery. His vital signs are normal, and he is feeding well. However, his ...

Combining the JAK inhibitor ruxolitinib with the BCL-xL inhibitor navitoclax was twice as effective in reducing enlarged spleens – a major indicator of clinical improvement – compared with standard-of ...

Spleen pain may feel like discomfort in the upper left side of the abdomen. It can occur for a range of reasons, including inflammation or injury. The treatment will depend on the underlying cause.