Loop diuretics are cornerstone therapies for the relief of congestion in patients with heart failure. By inhibiting the Na⁺‐K⁺‐2Cl⁻ cotransporter in the thick ascending limb of the loop of Henle, ...

Future Cardiol. 2012;8(5):707-728. These data come from reports of ototoxicity of 6.4% with furosemide compared with 1 and <1% for bumetanide and torsemide, respectively. [38] Acute kidney failure is ...

Diuretic therapy remains a cornerstone in the management of heart failure, targeting intravascular and interstitial volume overload to alleviate symptoms, improve exercise tolerance and reduce ...

Dapagliflozin (Farxiga) appears to be no more effective than the "thiazide-like" diuretic metolazone at improving pulmonary congestion and fluid status in patients with acute heart failure (AHF), ...

CHICAGO -- The choice between furosemide and torsemide didn't matter for longer-term clinical outcomes of hospitalized heart failure patients, according to the comparative effectiveness trial ...

BARCELONA, Spain—Patients with heart failure (HF) who are predicted to have a high risk of diuretic resistance tend to fare worse no matter whether they wind up taking furosemide or torsemide, with ...

Semaglutide reduces the need for loop diuretic use and dose, and has positive effects on symptoms, physical limitations, and body weight in patients with heart failure with preserved ejection fraction ...

Starting dapagliflozin (Farxiga) early during acute heart failure hospitalization didn't boost decongestion, although it appeared to spare loop diuretic doses and increase diuresis compared with usual ...