Botulinum neurotoxins (BoNT) have become a cornerstone in the treatment of hyperkinetic movement disorders, offering targeted and reversible ...
Neuromuscular disease refers to a group of heterogeneous disorders that impair the function of motor nerves, muscles or neuromuscular junctions. Symptoms can include muscle pain, weakness or atrophy, ...
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Background Intrathecal baclofen (ITB) is a useful treatment for hypertonia where non-invasive treatments have been ineffective or poorly tolerated. There is an absence of national guidance on ...
Introduction: Bladder and urinary sphincter malfunctioning that results from some change in the central and/or peripheral nervous system is defined as neurogenic bladder. The urinary tract symptoms ...
Correspondence to: Professor Alan J Thompson Institute of Neurology, Queen Square, London WC1N 3BG, UK; a.thompsonion.ucl.ac.uk Spasticity is a common symptom seen in many neurological conditions, ...
Background The evidence base to guide the pharmacological management of tone and abnormal movements in cerebral palsy (CP) is limited, as is an understanding of routine clinical practice in the UK. We ...
Sixty-eight blood pressure (BP)–lowering randomized controlled trials (defined as randomized controlled trials comparing active treatment with placebo, or less active treatment, achieving a BP ...