Fragile X disorders include two distinct conditions: fragile X syndrome (the most common single-gene cause of developmental ...

Intravenous thrombolysis remains a standard treatment for acute ischemic stroke within 4.5 hours after onset. Vascular reocclusion may occur after intravenous thrombolysis and may be preventable ...

In the current anti-immigrant political environment in the United States, what will happen when immigrants who work in the health care system are forced to leave?

As her patients near the end of life, an infectious disease physician who knows their stories sometimes needs to step out of her proverbial lane to help them assess and achieve their goals of care.

In 2006, a prospective observational study first showed that physical activity after a colon cancer diagnosis was linked to a decreased risk of recurrence and death.1 Since then, numerous observati ...

Cardiovascular diseases, principally ischemic heart disease and stroke, have consistently been the leading cause of death worldwide since 1990 and accounted for 19.8 million deaths in 2022 alone.1 ...

Prenatal genomic sequencing revealed congenital thrombotic thrombocytopenic purpura, enabling immediate plasma therapy. The case highlights the value and ethical complexity of reporting incidental ...

A 60-year-old man with hypertension and bipolar disorder was incidentally found to have small cysts on his kidneys during MRI of the abdomen.

A 64-year-old man presented with a 5-month history of a painful ulcer of the lateral left ankle. Recently, he had noticed malodorous secretions, increased erythema and edema, and worsening pain.

A 69-year-old man with multiple myeloma presented with an enlarging purple skin mass on his right shoulder at the surgical site of a recent intramedullary nailing of a humerus fracture.

Explore this issue of The New England Journal of Medicine (Vol. 392 No. 23).

Navigating cases of potential self-neglect is complicated for older adults and for the family members, clinicians, and social and legal services professionals involved in ensuring their well-being.