The Browns play host to the San Francisco 49ers in Shedeur Sanders' second start. Here's a look at the matchup, as well as key questions and stats.

McCaffrey has 10 games with at least five receptions and 100 scrimmage yards this season, the most in the league. He has 53 ...

San Francisco 49ers running back Christian McCaffrey explained the significance of Roger Craig and Frank Gore's impact on his ...

San Francisco 49ers TE George Kittle, RB Christian McCaffrey, FB Kyle Juszczyk, and T Trent Williams discussed their ...

Preview the player prop betting lines, stats and more for Christian McCaffrey before his San Francisco 49ers play the ...

For the three NFC West teams with postseason aspirations, Week 12 proved to be successful. They took care of business without ...

Could Khalil Shakir be poised for one of his biggest games of the year? Is DJ Moore playable again? Check out all of Michael ...

Should you trust Brock Purdy or Daniel Jones against stingy defenses? Check out all of Michael Florio's QB starts and sits ...

Christian McCaffrey gained 142 yards from scrimmage and scored a touchdown in his first game against Carolina since he was ...

Christian McCaffrey got revenge against the Carolina Panthers, leading the San Francisco 49ers to a 20-9 win against his ...

The 49ers improved to 8-4 overall and 8-2 in NFC competition, with their growing bond next tested Sunday in Cleveland.

The San Francisco 49ers (8-4) are on their way to Huntington Bank Field on Sunday where they will try to beat the Cleveland ...