The global pandemics of plague and smallpox in the Middle Ages claimed hundreds of millions of lives. In this era, long before the concepts of pathogens and infectious diseases were established, ...

Anticoagulation is a critical component in the treatment of cardiovascular diseases. Large randomised controlled trials have ...

Atrial fibrillation (AF) is the most common arrhythmia and is a leading cause of stroke and heart failure yet often remains undiagnosed. Screening has been proposed to identify asymptomatic AF and ...

10 The George Institute for Global Health, School of Public Health, Imperial College London, London, UK Background Cardiovascular risk is underassessed in women. Many women undergo screening ...

Obesity is an independent driver of cardiovascular disease (CVD), mediated through adverse haemodynamic loading, insulin resistance, systemic inflammation, endothelial dysfunction and prothrombotic ...

1 Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK 2 Department of Obstetrics and Gynaecology, University of Cambridge, Cambridge, UK Correspondence to Clare Teresa ...

Background Coronary microvascular dysfunction (CMD) is associated with a poor prognosis but is difficult to diagnose non-invasively. In a recent paper, ST-segment depression on exercise-ECG was found ...

Correspondence to Dr Nick Townsend, Nuffield Department of Population Health, British Heart Foundation Centre on Population Approaches for Non-Communicable Disease Prevention, Old Road Campus, ...

Background Socioeconomic disparities are associated with sudden cardiac arrest (SCA) in older populations, but evidence in young adults is limited. We investigated the association between income ...

We read with great interest the review by Yang et al on spontaneous coronary artery dissection (SCAD), which provides valuable insights into the current understanding and diagnosis of this challenging ...

Introduction Cardiovascular benefits deriving from physical activity are well known, but it is unclear whether physical activity trajectories in late life are associated with different risks of ...

Background Fluid restriction is a commonly prescribed non-pharmacological intervention in the management of heart failure (HF). However, data on its efficacy and safety are scarce. Recent randomised ...