Over the past decade, several tumor-based predictors of cetuximab efficacy have been identified, yet most function as ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Tank-binding kinase 1 (TBK1) is a Ser/Thr ...

Sphingosine kinase 1 is an agonist‐activated signalling enzyme that catalyses the formation of sphingosine 1‐phosphate, a lipid second messenger that has been implicated in a number of agonist‐driven ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Paraspeckles are constructed by NEAT1_2 ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. ER-phagy, a selective form of autophagic ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Atherosclerosis is characterized by the ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Alternative splicing (AS) leads to ...

Insertion of strongly hydrophobic TMDs into the ER membrane is mediated by the Sec61 complex for co‐translational insertion and the GET complex for post‐translational insertion of tail‐anchors ...

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Posttranslational modifications expand the diversity of the proteome enormously, with protein glycosylation being the most abundant and diverse form of modification serving different functions for ...

Each journal is staffed by professional editors who work in collaboration with one another and our international Editorial Advisory Boards of leading scientists. Please feel free to contact any of the ...

Mutations in fused in sarcoma (FUS) are a cause of familial amyotrophic lateral sclerosis (fALS). Patients carrying point mutations in the C‐terminus of FUS show neuronal cytoplasmic FUS‐positive ...